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IMDC intermediate/poor risk
Intention to treat
Characteristic
NIVO + IPI
N = 425
SUN
N = 422
NIVO + IPI
N = 550
SUN
N = 546
IMDC prognostic score (IVRS), %
Favorable (0)
Intermediate (1–2)
Poor (3–6)
0
79
21
0
79
21
23
61
17
23
61
16
Region (IVRS), %
USA
Canada/Europe
Rest of the world
26
35
39
26
35
39
28
37
35
28
36
36
Most common site of metastasis, %
Lung
Lymph node
Liver
Bone
69
45
21
20
70
51
21
21
69
45
18
18
68
49
20
19
Quantifiable tumor PD-L1 expression, %
<1%
≥1%
n = 384
74
26
n = 392
71
29
n = 499
77
23
n = 503
75
25
CHECKMATE 214 – PATIENTS CHARACTERISTICS
Motzer RJ, et al. N Engl J Med. 2018 Apr 5;378(14):1277-90