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• Timings of first occurrence of all grade TEAEs

Haddad I, et al. Endocrine. 2017;56:121–128.

Frequencies of these TEAEs were higher

in the earlier cycles and diminished over

the course of treatment

Median time to first onset:

12.1 weeks

Median time to first onset:

6.1 weeks

Median time to first onset:

3.0 weeks

Median time to first onset:

7.3 weeks

Median time to first onset:

5.9 weeks

Maximization of treatment results