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FRAGANCE Study: Efficacy of
nab
-paclitaxel
+ Gem in ECOG PS2 Advanced PC
Arm C
Median 7.8 months
;
95%CI (8.4-9.1)
Arm E
Median 9.8 months;
95%CI (7.9-11.8)
Arm C
Median 5.5 months
;
95%CI (4.1-6.9)
Arm E
Median 6.7 months;
95%CI (5.7-7.7)
Overall Survival
Progression Free Survival
MPACT mOS
8.5 months
MPACT mPFS
5.5 months
MPACT ORR 23%
•
Combination chemotherapy is feasible and results are comparable to
those in MPACT trial in patiets with PS 0-1
Hidalgo M, et al.
Ann Oncol
. 2017;28(Suppl 5):Abstract 623PD.