Optimizando el tratamiento en Cáncer de Páncreas Metastásico

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Eyraspase (eritrocite encapsulated L-asparaginase)
1.- Hammel et al, ESMO 2017
Rand CT +/- Eyraspase
in 2nd line mPC 1
140 pts (97 pts ASNS 0/1+)
CT: Gem in 90% of pts
.- 1º endpoint PFS/OS in 97 pts ASNS 0/1+
HR: PFS 0.73 ; OS 0.62
.- 2º endpoint OS in the ITT population (140 pts)
median OS 26.1 w vs 19 w (HR, 0.57; P = .03).