19 / 36
Frecuencia de aparición de AEs
con el tiempo de exposición
19
• In the first 3 months of treatment, the exposure-adjusted AE occurrence rate per patient treated with
dabrafenib plus trametinib was 6.14 AEs/patient/3 months of exposure; AE occurrences declined
substantially with increased duration of treatment
AE, adverse event
Atkinson V, et al. ESMO 2018