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XSG: 5,2 m. vs 3,8 m.; HR:0,77 (0,6-0,99); p=0.047

SG 6 meses: 41% vs 8%; SG 12 meses: 17% vs 11%

XSLP: 2,1 m vs 1,3 m; SLP 12 semanas: 40% vs 15%

Ramucirumab vs BSC: REGARD

Fuchs et al. Lancet 2014; 383:31