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Overall Survival, %

Time (months)

0

10

20

30

40

50

60

70

80

90

100

0 3 6 9 12

21 24 27

36 39 42

48

15 18

30 33

45

ENCO300

VEM

Censored patients

Overall Survival

è

ENCO300 vs VEM

Median OS in months (95% CI)

ENCO300

VEM

23.5 (19.6–33.6)

16.9 (14.0–24.5)

HR (95% CI), 0.76 (0.58–0.98)

Nominal 2-sided

P

=0.033

Reinhard Dummer