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Incorporating Bevacizumab and Erlotib in the combined-modality

treatment of stage III NSCLC: Results of a phase I/II trial

Trial

LCCC

9603

LCCC

2001

LCCC

0215

CALGB

30105

RTOG

0324

CALGB

30407

Socinski

2012

Nº p

62

29

23

43

87

101

45

Induction

QT

CbP CbP CbPI

CbP -

-

CbP

Beva

Concurrent

CbP CbP CbP+

gefitinib

CbP CbP +

Cetuxi

CbPem

+/-

Cetuxi

CbP

Beva

+

Erlotinib

TCRT, Gy

60-74 78-90 74

74

63

70

74

PFS rate 1

year, %

47

45

40

55

50

50

44

Median S,

m

26

24

16

24,3

22,7

21-25

18,4

Esophagiti

s,G 3 /4 %

8

16

19,5

16

8

13-16

29