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Cabozantinib en 1L: Cabosun

Characteristic

Cabozantinib (n=79)

Sunitinib (n=78)

Median age, years (range)

63 (56–69)

64 (57–71)

Male, %

84

73

ECOG performance status, %

0/1/2

46/42/13

46/41/13

IMDC risk group,

a

%

Intermediate/poor

81/19

81/19

Prior nephrectomy, %

72

77

Bone metastases, %

37

36

Positive MET status,

b

%

41

38

No. metastatic sites per investigator, %

1/2/≥3

22/47/32

33/26/41

Metastatic sites per investigator, %

Nodal

57

54

Lung

70

69

Liver

19

26

Bone

39

38

CNS/brain

4

3

Características de los pacientes