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Pmab→VEGFi

(n=58)

VEGFi→Pmab

(n=35)

OS median (95%CI)

months

41.3

(31.6-46.1)

28.9

(24.2-39.2)

HR (95%CI)

0.58 (0.36-0.95)

P-value

0.03

Pmab→VEGFi

(n=66)

VEGFi→Pmab

(n=38)

OS median

(95%CI) months

36.8

(30.3-43.8)

27.8

(24.2-35.6)

HR (95%CI)

0.65 (0.42-1.03)

P-value

0.06

SG según la secuencia de tratamiento

RAS WT

RAS WT BRAF WT

Peeters M et al. ESMO Open 2018;3:e000297 DOI: 10.1136/esmoopen-2017-000297