13 / 40
Tratamiento
Doxo
Dox-Ifo
Dosis
75mg/m2/3w 75mg/m2+ifo 10g/m2/3
N
217
215
mCiclos
5
6
mDosis (equiv)
375
450
RR local/central
13.6
26.5%
PFS
4.6m
7.4m
pvalor
0.003
Neutropenia (febril)
37%(13%)
41(45%)
mOS
12.8
14.3
Ifosfamida
TXT-gem
Trabectedina
Buy-Nguyen
Eur J
Cancer.
2015
Judson. The Lancet Oncology. 2014
Seddon, J ASCO 2015
Doxorrubicina
TRATAMIENTO: SPB